Choosing the appropriate lubricant

Decision guide: Choosing between INSTILLAGEL^® and JELIDO^®^1–3

Feature

Lubrication

Local anaesthetic
(2% lidocaine)

Contains antiseptic
(0.05% chlorhexidine)

The selection of an appropriate lubricant also depends on its intended use, as different products are indicated for different clinical applications.^1,2

INSTILLAGEL^® (lidocaine and chlorhexidine gel) is indicated for surface anaesthesia, lubrication, and antisepsis for:¹

The male and female urethra during cystoscopy
Catheterization
Exploration by sound and other endourethral operations

JELIDO

JELIDO^® (lidocaine hydrochloride jelly) is indicated for:²

Surface anaesthesia and lubrication for:
- The male and female urethra during cystoscopy, catheterization, exploration by sound, and other endourethral operations;
- Nasal and pharyngeal cavities in endoscopic procedures such as gastroscopy and bronchoscopy;
- Proctoscopy and rectoscopy;
- Tracheal intubation.
Symptomatic treatment of pain in connection with cystitis and urethritis.

Comparing key ingredients^1,2

Both INSTILLAGEL^® and JELIDO^® provide:^1,2

Protective, uniform LUBRICATION

May reduce the risk of injury during instrumentation⁴

Rapid, lasting, ANAESTHETIC action^†,‡

Contains 2%
lidocaine hydrochloride
Anaesthetizes within 5 to 10 minutes and lasts approximately 20 to
30 minutes

INSTILLAGEL^® offers the added benefit of:¹

ANTISEPTIC properties

Contains 0.05% chlorhexidine gluconate
Effective protection against a wide spectrum of microorganisms
Especially useful for urological interventions

Analgesic properties of INSTILLAGEL^® and JELIDO^®^1,2

Lidocaine is an amide-type local anaesthetic. In both INSTILLAGEL^® and JELIDO^®, it is used at a 2% concentration.^§,1,2

Anaesthesia is typically achieved within 5 minutes, depending on the site of application, and lasts for approximately 20 to 30 minutes.^1,2

May reduce risk of endourethral injury because the anaesthetic action reduces pain, which may subsequently reduce patient movement such as tensing or flinching^4,5

Antiseptic properties of INSTILLAGEL^®¹

When infection prevention is required, a lubricant containing chlorhexidine may offer added benefit. Chlorhexidine demonstrated broad-spectrum antimicrobial activity.¹

The antiseptic effect is achieved within approximately 5–10 minutes. This activity helps reduce the risk
of microbial microorganisms ascent or upward displacement following urological procedures.

Both INSTILLAGEL^® and JELIDO^® feature the same FARCO^®* syringe design^1,2,6

Innovative UROSAFETIP^®1,2,6

The innovative UROSAFETIP^®
tip design helps reduce the risk of injury and supports patient comfort

Easy to use, pre-assembled, pre-filled, sterile syringe^1,2,6

INSTILLAGEL^® offers an easy-to-use, one-handed, pre-filled syringe

Manufactured in GMP-compliant facilities, INSTILLAGEL^® and JELIDO^® deliver consistent product quality you can trust.

Optimized packaging material for more sustainability⁶

Illustration of packaging dimensions for 10 syringes

Schematic illustration of a 10-syringe carton. The illustration depicts the underside (bottom view) of the carton. The grey rectangles represent individual syringe packages, while the surrounding box represents the outer carton containing all 10 syringes.

INSTILLAGEL^®

STORAGE

Reduced packaging = smaller footprint on shelves

WASTE

Less packaging = less waste

TIME

Removal from package is simple and quick

Learn how the pre-filled FARCO^®* syringe performs

Explore

Want to know more about JELIDO^®?

Learn more

INSTILLAGEL^® (lidocaine and chlorhexidine gel) is indicated for surface anaesthesia, lubrication, and antisepsis for:¹

The male and female urethra during cystoscopy
Catheterization
Exploration by sound and other endourethral operations

for additional safety information and for a link to the Prescribing Information, which discusses:

Contraindications in children < 2 years of age and in patients with a known or suspected hypersensitivity to this drug or any component of the formulation.
Most serious warnings and precautions regarding: use in urethra only (not for parenteral administration) and immediate systemic hypersensitivity reactions.
Other relevant warnings and precautions regarding: use of the lowest effective dose; avoiding contact with eyes and middle ear; familial malignant hyperthermia; carcinogenesis and mutagenesis; excessive hypotensive response; use during early pregnancy (first trimester); and dose reduction in children, debilitated patients, acutely ill patients, and patients with sepsis. Use with caution in patients with: severe shock; sepsis and/or traumatized mucosa at the application site; epilepsy; impaired cardiac conduction; bradycardia; impaired cardiovascular function; impaired hepatic or renal function; and in persons with known drug sensitivities.
Conditions of clinical use, adverse reactions, drug interactions, and dosing instructions.

JELIDO^® (lidocaine hydrochloride jelly) is indicated for:²

Surface anaesthesia and lubrication for:
- The male and female urethra during cystoscopy, catheterization, exploration by sound, and other endourethral operations;
- Nasal and pharyngeal cavities in endoscopic procedures such as gastroscopy and bronchoscopy;
- Proctoscopy and rectoscopy;
- Tracheal intubation.
Symptomatic treatment of pain in connection with cystitis and urethritis

Click here for additional safety information and for a link to the Product Monograph, which discusses:

Contraindications in patients with: a hypersensitivity to this drug or any ingredient in the formulation; a known history of hypersensitivity to amide-type local anaesthetics or other formulation components; congenital or idiopathic methemoglobinemia; a need for treatment with methemoglobin-inducing agents (e.g., sulfonamides) in infants ≤ 12 months of age; or, glucose-6-phosphate dehydrogenase deficiency
Most serious warnings and precautions regarding: adherence to the recommended dosage; and use in children and infants (< 3 months of age)
Other relevant warnings and precautions regarding: use of the lowest effective dose; avoiding contact with eyes; familial malignant hyperthermia; increased plasma concentrations in patients under general anaesthesia; use in unparalyzed patients; endotracheal tube lubrication; risk of aspiration; unintentional biting trauma; impairment of locomotion or alertness; caution when driving and operating machinery; and use in patients with porphyria. Use with caution in patients with: sepsis; traumatized mucosa at the application site; epilepsy; severe shock; bradycardia; impaired cardiovascular function; hepatic disease or impaired renal function; or known drug sensitivities. Reduced doses should be given in debilitated patients, acutely ill patients, and patients with sepsis. Care should be taken during early pregnancy.
Conditions of clinical use, adverse reactions, drug interactions, and dosing instructions

d: depth; h: height; w: width
†In order to obtain adequate anaesthesia and antiseptic action, 5 to 10 minutes should be allowed prior to performing urethral procedures.
‡Duration of anaesthesia is approximately 20 to 30 minutes.
§Of the 350 million applications of INSTILLAGEL^®, 59 spontaneous adverse drug reactions have been reported to the manufacturer. Of these, 9 were anaphylactic reactions, 3 were allergic reactions, and 10 were local discomfort.

References: 1. INSTILLAGEL^® Prescribing Information. PENDOPHARM^®, Division of Pharmascience Inc. February 19, 2025. 2. JELIDO^® Product Monograph. PENDOPHARM^®, Division of Pharmascience Inc. February 19, 2026. 3. Wilson M. Catheter lubrication and fixation: interventions. Br J Nurs. 2013 May 23–Jun 12;22(10):566, 568–9. 4. Sperling H, Lümmen G, Rübben H. The use of lubricants in urology. Indications and results. Urologe [A] 2005;44(6):662–666. 5. Muctar S. [The importance of a lubricant in transurethral interventions]. Urologe. [B] 1991;31:153–155. 6. Data on file. PENDOPHARM^®, Division of Pharmascience Inc.

Choosing the appropriate lubricant